NCLEX-RN Sample Questions and Explanations
No published past questions are available for this exam yet. Instead, here are 10 of our 128 AI-written NCLEX-RN practice questions, chosen to match the question types that come up most.
The NCLEX RN exam covers Safe and Effective Care Environment (26), Health Promotion and Maintenance (8), Psychosocial Integrity (8), Physiological Integrity (43), 85 questions in total. New to 'NCLEX'? Read these first to see what to expect.
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NCLEX-RN: 10 sample questions
Question 1. The RN is caring for a group of clients on a medical-surgical unit. Which task is most appropriate for the RN to delegate to an unlicensed assistive personnel (UAP)?
- ① Measuring vital signs on a stable client 2 days after hip surgery
- ② Completing the skin assessment for a newly admitted client
- ③ Teaching a client how to use an incentive spirometer
- ④ Giving a scheduled oral medication to a client with heart failure
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Answer: ① Measuring vital signs on a stable client 2 days after hip surgery
Key point: UAP: routine care for stable clients; RN keeps assess, teach, evaluate
A UAP (such as a nursing assistant) can do routine, predictable tasks for clients who are stable. Taking vital signs on a stable client 2 days after surgery fits this rule. The RN still reviews the numbers and acts on anything abnormal.
A simple way to remember what the RN keeps: assessment, teaching, evaluation, and nursing judgment cannot be delegated to a UAP.
Wrong choices
- "Teaching a client how to use an incentive spirometer": Teaching is an RN responsibility. A UAP can remind a client to use it, but cannot do the teaching.
- "Completing the skin assessment": Assessment, especially on admission, needs nursing judgment and stays with the RN.
- "Giving a scheduled oral medication": Giving medications is outside the UAP role.
Question 2. A parent asks why the newborn needs a vitamin K injection soon after birth. Which response by the nurse is correct?
- ① "It helps lower the chance of newborn jaundice."
- ② "It protects your baby from hepatitis B."
- ③ "Newborns do not yet have enough vitamin K to help their blood clot."
- ④ "It protects your baby's eyes from infection."
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Answer: ③ "Newborns do not yet have enough vitamin K to help their blood clot."
Key point: Vitamin K shot prevents bleeding in newborns
Newborns are born with low vitamin K, and their gut does not yet have the bacteria that make it. Vitamin K is needed for blood to clot. One injection soon after birth prevents vitamin K deficiency bleeding, a rare but serious bleeding problem that can affect the brain.
Wrong choices
- "It protects your baby's eyes from infection" describes the eye ointment (erythromycin), not vitamin K.
- "It helps lower the chance of newborn jaundice" is not correct. Jaundice is managed with feeding and, if needed, light therapy.
- "It protects your baby from hepatitis B" describes the hepatitis B vaccine, a different injection.
Question 3. A client takes lithium for bipolar disorder. Which finding should the nurse report as a possible early sign of lithium toxicity?
- ① Mild thirst when starting the medicine
- ② Increased appetite
- ③ Feeling calmer than last week
- ④ Vomiting and diarrhea
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Answer: ④ Vomiting and diarrhea
Key point: Vomiting, diarrhea, and a worsening tremor can signal lithium toxicity
Lithium has a narrow safe range in the blood. Early signs of toxicity include nausea, vomiting, diarrhea, and a worsening hand tremor. Vomiting and diarrhea also cause fluid and sodium loss, which can raise the lithium level even more. The nurse should hold the dose and report the finding so the level can be checked.
Wrong choices
- "Feeling calmer than last week" is the expected effect of treatment.
- "Mild thirst when starting the medicine" is a common side effect, not a sign of toxicity on its own.
- "Increased appetite" can occur with lithium and is not a sign of toxicity.
Question 4. A client receiving a continuous IV heparin infusion develops bleeding from the gums and new blood in the urine. The provider stops the heparin. Which medication does the nurse expect to be ordered to reverse the heparin?
- ① Flumazenil
- ② Naloxone
- ③ Protamine sulfate
- ④ Vitamin K (phytonadione)
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Answer: ③ Protamine sulfate
Key point: Protamine sulfate reverses heparin; vitamin K reverses warfarin
Heparin is a high-alert blood thinner. When a client on heparin shows signs of serious bleeding, the drug is stopped and protamine sulfate may be given. Protamine binds to heparin in the blood and makes it inactive within minutes.
It helps to remember the pairs:
- Heparin → protamine sulfate
- Warfarin → vitamin K (phytonadione)
- Opioids → naloxone
- Benzodiazepines → flumazenil
Wrong choices
- "Vitamin K": this reverses warfarin, not heparin. It works slowly, over hours.
- "Naloxone": reverses opioids such as morphine. It has no effect on bleeding.
- "Flumazenil": reverses benzodiazepines such as lorazepam. It has no effect on bleeding.
Question 5. The surgeon has explained a planned surgery to a client. The client agrees and is ready to sign the consent form. What is the nurse's role in this process?
- ① Witness that the client signed the form voluntarily
- ② Decide whether the client truly needs the surgery
- ③ Have the client's adult child sign the form for the client
- ④ Explain the risks and benefits of the surgery to the client
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Answer: ① Witness that the client signed the form voluntarily
Key point: Provider explains consent; nurse witnesses the signature
Getting informed consent is the provider's job (the surgeon or the person doing the procedure). The provider explains the procedure, risks, benefits, and other options.
The nurse's role is to witness the signature. This means the nurse confirms that the person signing is the client, that the client signed of their own free will, and that the client appears able to make the decision. If the client has questions, the nurse contacts the provider.
Wrong choices
- "Explain the risks and benefits": This is the provider's duty, not the nurse's.
- "Decide whether the client truly needs the surgery": The nurse does not decide medical treatment.
- "Have the client's adult child sign": A competent adult signs their own consent. A family member signs only if the client cannot legally make the decision and that person is the legal decision-maker.
Question 6. A pregnant client asks which vaccines are safe during pregnancy. Which vaccine should NOT be given during pregnancy?
- ① Measles, mumps, and rubella (MMR)
- ② Hepatitis B
- ③ Tdap (tetanus, diphtheria, and pertussis)
- ④ Inactivated influenza (flu shot)
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Answer: ① Measles, mumps, and rubella (MMR)
Key point: Live vaccines such as MMR are not given during pregnancy
MMR is a live vaccine (it contains weakened live virus). Live vaccines are not given during pregnancy because of a possible risk to the baby. A client who is not immune to rubella is usually given MMR after the baby is born.
Wrong choices
- "Tdap" is an inactivated vaccine and is recommended during each pregnancy to protect the newborn from whooping cough.
- "Inactivated influenza (flu shot)" is recommended during pregnancy because flu can be serious for pregnant clients.
- "Hepatitis B" is not a live vaccine; certain hepatitis B vaccine brands are recommended during pregnancy for clients at risk.
Question 7. A client says, "I'm really scared about my surgery tomorrow." Which response by the nurse is most therapeutic?
- ① "Everyone feels that way before surgery."
- ② "Why are you scared?"
- ③ "Don't worry. Your surgeon is excellent."
- ④ "Tell me more about what is worrying you."
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Answer: ④ "Tell me more about what is worrying you."
Key point: Open-ended questions invite clients to share feelings
An open-ended statement such as "Tell me more" invites the client to talk about the fear. This helps the nurse learn what the client is worried about (pain, anesthesia, results) and give the right support or information.
Wrong choices
- "Don't worry. Your surgeon is excellent" is false reassurance. It brushes off the client's feelings.
- "Why are you scared?" asks "why," which can make the client feel they must defend their feelings.
- "Everyone feels that way" generalizes and makes the client's feelings seem unimportant.
Question 8. A client is taking warfarin at home to prevent clots from atrial fibrillation. Which lab test does the nurse use to check whether the warfarin dose is working safely?
- ① Activated partial thromboplastin time (aPTT)
- ② Platelet count
- ③ International normalized ratio (INR)
- ④ Serum potassium
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Answer: ③ International normalized ratio (INR)
Key point: Warfarin is monitored with the INR (PT/INR)
Warfarin slows the liver's use of vitamin K to make clotting factors. Its effect is measured with the prothrombin time (PT), reported as the INR (international normalized ratio). The INR lets results be compared between labs. The provider sets the target INR for each client, and the dose is adjusted to keep the client in that range.
An INR above the target means a higher bleeding risk. An INR below the target means the client is less protected from clots.
Wrong choices
- "aPTT": this is used to monitor IV heparin, not warfarin. Mixing up these two tests is a common error.
- "Platelet count": important to watch with heparin (for heparin-induced thrombocytopenia), but it does not show warfarin's effect.
- "Serum potassium": not related to warfarin's effect on clotting.
Question 9. A nurse is leaving the room of a client with Clostridioides difficile (C. diff) infection. Which hand hygiene method should the nurse use?
- ① Washing with soap and water
- ② Removing gloves without any hand hygiene
- ③ Alcohol-based hand rub
- ④ Wiping hands with a disinfectant wipe for equipment
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Answer: ① Washing with soap and water
Key point: C. diff spores: wash hands with soap and water
C. diff forms spores (a tough, protected form of the germ). Alcohol does not kill these spores well. Washing with soap and running water physically rubs and rinses them off the hands.
So for C. diff, the nurse wears gloves and a gown (contact precautions) and then washes hands with soap and water after care.
Wrong choices
- "Alcohol-based hand rub": Alcohol rub is fine for most germs but does not work well against C. diff spores.
- "Removing gloves without any hand hygiene": Hand hygiene is always needed after removing gloves; gloves can have tiny holes or contaminate hands while being removed.
- "Wiping hands with a disinfectant wipe for equipment": Equipment wipes are not made for skin and can harm it.
Question 10. The nurse has taught a client how to draw up and inject insulin. Which action best shows that the client has learned the skill?
- ① The client says, "Yes, I understand."
- ② The client watches a video about insulin
- ③ The client takes home a printed handout
- ④ The client shows the nurse how to draw up and inject the insulin
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Answer: ④ The client shows the nurse how to draw up and inject the insulin
Key point: Return demonstration best confirms learning of a skill
For a hands-on skill, the best way to check learning is a return demonstration: the client does the skill while the nurse watches. The nurse can see mistakes and correct them before the client goes home.
Wrong choices
- "Yes, I understand" does not prove the client can do the skill. Many people say yes even when they are unsure.
- "Takes home a printed handout" is a helpful extra but does not show the client can do it.
- "Watches a video about insulin" is a teaching method, not a way to check learning.
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